8B4M

Crystal structure of a hydropyrene synthase (M75L variant) in its closed conformation

Summary for 8B4M

Entry DOI	10.2210/pdb8b4m/pdb
Related	8B4L
Descriptor	Terpene synthase, MAGNESIUM ION, ALENDRONATE (3 entities in total)
Functional Keywords	diterpene synthase, pseudopterosins, ggdp, hydropyrene synthase, lyase
Biological source	Streptomyces clavuligerus
Total number of polymer chains	6
Total formula weight	217121.99
Authors	Helmer, C.P.O.,Driller, R.,Loll, B. (deposition date: 2022-09-20, release date: 2023-10-04, Last modification date: 2026-03-25)
Primary citation	Ringel, M.,Helmer, C.P.O.,Zev, S.,Driller, R.,Buhr, E.,Reinbold, M.,Schwartz, R.,Foley, G.,Boden, M.,Garbe, D.,Schenk, G.,Major, D.T.,Loll, B.,Bruck, T. A methionine-lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase Febs Lett., 2026 Cited by DOI: 10.1002/1873-3468.70325 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.04 Å)

Structure validation