8B3Z

SigE N-terminal Domain

8B3Z の概要

• エントリーDOI: 10.2210/pdb8b3z/pdb
• 分子名称: RNA polymerase sigma factor (2 entities in total)
• 機能のキーワード: sigma factor, dna binding protein
• 由来する生物種: Bacillus subtilis
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 56406.13

構造登録者

Evans, N.J.,Isaacson, R.L.,Collins, K.M.,Camp, A.H. (登録日: 2022-09-18, 公開日: 2023-08-23, 最終更新日: 2026-03-04)

主引用文献

Collins, K.M.,Evans, N.J.,Torpey, J.H.,Harris, J.M.,Haynes, B.A.,Camp, A.H.,Isaacson, R.L.
Structural Analysis of Bacillus subtilis Sigma Factors.
Microorganisms, 11:-, 2023

PubMed Abstract: Bacteria use an array of sigma factors to regulate gene expression during different stages of their life cycles. Full-length, atomic-level structures of sigma factors have been challenging to obtain experimentally as a result of their many regions of intrinsic disorder. AlphaFold has now supplied plausible full-length models for most sigma factors. Here we discuss the current understanding of the structures and functions of sigma factors in the model organism, , and present an X-ray crystal structure of a region of SigE, a sigma factor that plays a critical role in the developmental process of spore formation.

PubMed: 37110501
DOI: 10.3390/microorganisms11041077

実験手法

X-RAY DIFFRACTION (2.38 Å)