8AXC

Crystal structure of mouse Ces2c

8AXC の概要

• エントリーDOI: 10.2210/pdb8axc/pdb
• 分子名称: Acylcarnitine hydrolase, CHLORIDE ION, NICOTINAMIDE, ... (5 entities in total)
• 機能のキーワード: carboxylesterase 2c; protein structure; lipid metabolism; x-ray crystallography; alpha/beta-hydrolase fold; biochemistry; lipid hydrolysis; non-alcoholic fatty liver disease; molnupiravir, hydrolase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 251099.98

構造登録者

Eisner, H.,Riegler-Berket, L.,Rodriguez Gamez, C.,Sagmeister, T.,Chalhoub, G.,Darnhofer, B.,Panikkaveetil Jawaharlal, J.,Birner-Gruenberger, R.,Pavkov-Keller, T.,Haemmerle, G.,Schoiswohl, G.,Oberer, M. (登録日: 2022-08-31, 公開日: 2022-11-16, 最終更新日: 2024-01-31)

• 主引用文献: Eisner, H.,Riegler-Berket, L.,Gamez, C.F.R.,Sagmeister, T.,Chalhoub, G.,Darnhofer, B.,Jazleena, P.J.,Birner-Gruenberger, R.,Pavkov-Keller, T.,Haemmerle, G.,Schoiswohl, G.,Oberer, M.; The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1.; Int J Mol Sci, 23:-, 2022; PubMed: 36361897; DOI: 10.3390/ijms232113101

実験手法

X-RAY DIFFRACTION (2.12 Å)