8ATH

CRYSTAL STRUCTURE OF LAMP1 IN COMPLEX WITH FAB-B.

Summary for 8ATH

Entry DOI	10.2210/pdb8ath/pdb
Descriptor	Lysosome-associated membrane glycoprotein 1, Fab B Heavy Chain, Fab B Light Chain, ... (4 entities in total)
Functional Keywords	antigen, fab, complex, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	134706.15
Authors	Mathieu, M.,Dupuy, A. (deposition date: 2022-08-23, release date: 2023-03-01, Last modification date: 2024-05-01)
Primary citation	Pruvost, T.,Mathieu, M.,Dubois, S.,Maillere, B.,Vigne, E.,Nozach, H. Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold. Mabs, 15:2175311-2175311, 2023 Cited by PubMed: 36797224 DOI: 10.1080/19420862.2023.2175311 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.366 Å)

Structure validation