8ASE
Crystal structure of Thrombin in complex with macrocycle T3
Summary for 8ASE
Entry DOI | 10.2210/pdb8ase/pdb |
Descriptor | Thrombin light chain, Thrombin heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | serine endopeptidases, alpha-thrombin, activated factor iia, fibrinogenase, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 69763.66 |
Authors | Chinellato, M.,Angelini, A.,Nielsen, A.,Heinis, C.,Cendron, L. (deposition date: 2022-08-19, release date: 2023-11-29) |
Primary citation | Nielsen, A.,Chinellato, M.,Cendron, L.,Angelini, A.,Heinis, C. Crystal structure of Thrombin in complex with optimized macrocycles T1 and T3 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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