8AON
Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody
This is a non-PDB format compatible entry.
Summary for 8AON
Entry DOI | 10.2210/pdb8aon/pdb |
Related | 4IJ3 5D96 |
Descriptor | Oxidoreductase fragment of human QSOX1, Heavy chain, Light chain, ... (5 entities in total) |
Functional Keywords | antibody, humanized, fab, qsox1, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 74361.47 |
Authors | Khmelnitsky, L.,Fass, D. (deposition date: 2022-08-08, release date: 2023-08-02, Last modification date: 2024-10-16) |
Primary citation | Tennenhouse, A.,Khmelnitsky, L.,Yeshaya, N.,Noronha, A.,Lindzen, M.,Khalaila, R.,Zaretsky, I.,Fridmann Sirkis, Y.,Galon-Wolfenson, Y.,Abramson, J.,Yarden, Y.,Fass, D.,Fleishman, S.J. Reliable energy-based antibody humanization and stabilization To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report