8AN4

MenT1 toxin (rv0078a) from Mycobacterium tuberculosis H37Rv

Summary for 8AN4

Entry DOI	10.2210/pdb8an4/pdb
Descriptor	Bacterial toxin (2 entities in total)
Functional Keywords	toxin-antitoxin tuberculosis nucleotidyltransferase ment menat, toxin
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	2
Total formula weight	43018.74
Authors	Xu, X.,Usher, B.,Gutierrez, C.,Barriot, R.,Arrowsmith, T.J.,Han, X.,Redder, P.,Neyrolles, O.,Blower, T.R.,Genevaux, P. (deposition date: 2022-08-04, release date: 2023-08-02, Last modification date: 2023-08-30)
Primary citation	Xu, X.,Usher, B.,Gutierrez, C.,Barriot, R.,Arrowsmith, T.J.,Han, X.,Redder, P.,Neyrolles, O.,Blower, T.R.,Genevaux, P. MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding. Nat Commun, 14:4644-4644, 2023 Cited by PubMed: 37591829 DOI: 10.1038/s41467-023-40264-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation