8ALQ

The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2 that Binds to Asymmetrically Modified DNA

8ALQ の概要

• エントリーDOI: 10.2210/pdb8alq/pdb
• NMR情報: BMRB: 34745
• 分子名称: Methyl-CpG-binding protein 2 (1 entity in total)
• 機能のキーワード: hmc-mc complex, gene regulation, methyl-cpg-binding domain (mbd) of mecp2, dna binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11905.29

構造登録者

Singh, H. (登録日: 2022-08-01, 公開日: 2023-02-22, 最終更新日: 2024-06-19)

• 主引用文献: Singh, H.,Das, C.K.,Buchmuller, B.C.,Schafer, L.V.,Summerer, D.,Linser, R.; Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity.; Nucleic Acids Res., 51:6495-6506, 2023; PubMed: 36919612; DOI: 10.1093/nar/gkad134

実験手法

SOLUTION NMR