8AHE

PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery

Summary for 8AHE

• Entry DOI: 10.2210/pdb8ahe/pdb
• Descriptor: UDP-N-acetylglucosamine 2-epimerase, ~{N},5-dimethyl-1-phenyl-pyrazole-4-sulfonamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: inhibitor, complex, epimerase, technology, isomerase
• Biological source: Bacillus anthracis
• Total number of polymer chains: 2
• Total formula weight: 85203.14

Authors

Baker, L.M.,Murray, J.B.,Hubbard, R.E. (deposition date: 2022-07-21, release date: 2022-09-14, Last modification date: 2024-01-31)

• Primary citation: Ma, H.,Murray, J.B.,Luo, H.,Cheng, X.,Chen, Q.,Song, C.,Duan, C.,Tan, P.,Zhang, L.,Liu, J.,Morgan, B.A.,Li, J.,Wan, J.,Baker, L.M.,Finnie, W.,Guetzoyan, L.,Harris, R.,Hendrickson, N.,Matassova, N.,Simmonite, H.,Smith, J.,Hubbard, R.E.,Liu, G.; PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery.; Rsc Med Chem, 13:1341-1349, 2022; PubMed: 36426238; DOI: 10.1039/d2md00197g

Experimental method

X-RAY DIFFRACTION (2.108 Å)