8AGK

Botulinum neurotoxin subtype A6 cell binding domain in complex with GD1a ganglioside

これはPDB形式変換不可エントリーです。

8AGK の概要

• エントリーDOI: 10.2210/pdb8agk/pdb
• 分子名称: Bont/A1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-alpha-D-galactopyranose-(1-4)-alpha-D-glucopyranose, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: botulism, ganglioside, botulinum neurotoxin, cell binding domain, complex, subtype, toxin
• 由来する生物種: Clostridium botulinum str. Iwanei E
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52309.23

構造登録者

Gregory, K.S.,Acharya, K.R.,Liu, S.M.,Newell, A.R.,Mojanaga, O.O. (登録日: 2022-07-20, 公開日: 2022-09-21, 最終更新日: 2024-01-31)

• 主引用文献: Gregory, K.S.,Newell, A.R.,Mojanaga, O.O.,Liu, S.M.,Acharya, K.R.; Crystal Structures of the Clostridium botulinum Neurotoxin A6 Cell Binding Domain Alone and in Complex with GD1a Reveal Significant Conformational Flexibility.; Int J Mol Sci, 23:-, 2022; PubMed: 36077016; DOI: 10.3390/ijms23179620

実験手法

X-RAY DIFFRACTION (1.5 Å)