8ADQ

Crystal structure of holo-SwHPA-Mg (hydroxy ketone aldolase) from Sphingomonas wittichii RW1 in complex with hydroxypyruvate and D-Glyceraldehyde

8ADQ の概要

• エントリーDOI: 10.2210/pdb8adq/pdb
• 分子名称: HpcH/HpaI aldolase, 3-HYDROXYPYRUVIC ACID, D-Glyceraldehyde, ... (8 entities in total)
• 機能のキーワード: hydroxy-keto aldolase; aldol condensation; aldol cleavage; stereospecificity; tim barrel fold, lyase
• 由来する生物種: Rhizorhabdus wittichii RW1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28586.24

構造登録者

Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (登録日: 2022-07-11, 公開日: 2022-11-23, 最終更新日: 2024-01-31)

• 主引用文献: Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U.; Substrate Induced Movement of the Metal Cofactor between Active and Resting State.; Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022; PubMed: 36214476; DOI: 10.1002/anie.202213338

実験手法

X-RAY DIFFRACTION (1.6 Å)