8ABS

Crystal structure of CYP109A2 from Bacillus megaterium bound with testosterone and putative ligand 4,6-dimethyloctanoic acid

8ABS の概要

• エントリーDOI: 10.2210/pdb8abs/pdb
• 分子名称: Cytochrome P450, HEME B/C, (4~{S},6~{S})-4,6-dimethyloctanoic acid, ... (6 entities in total)
• 機能のキーワード: cytochrome p450, testosterone, fatty acid, steroid, complex, oxidoreductase
• 由来する生物種: Priestia megaterium DSM 319
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48641.96

構造登録者

Jozwik, I.K.,Rozeboom, H.J.,Thunnissen, A.-M.W.H. (登録日: 2022-07-04, 公開日: 2023-07-12, 最終更新日: 2024-02-07)

• 主引用文献: Jozwik, I.K.,Bombino, E.,Abdulmughni, A.,Hartz, P.,Rozeboom, H.J.,Wijma, H.J.,Kappl, R.,Janssen, D.B.,Bernhardt, R.,Thunnissen, A.W.H.; Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling.; Febs J., 290:5016-5035, 2023; PubMed: 37453052; DOI: 10.1111/febs.16906

実験手法

X-RAY DIFFRACTION (1.75 Å)