8AAS

Crystal structure of the Pyrococcus abyssi RPA trimerization core bound to poly-dT20 ssDNA

8AAS の概要

• エントリーDOI: 10.2210/pdb8aas/pdb
• 分子名称: Replication factor A, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, ... (6 entities in total)
• 機能のキーワード: replication protein a, ssdna-binding protein, dna binding protein
• 由来する生物種: Pyrococcus abyssi GE5; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75348.16

構造登録者

Madru, C.,Legrand, P.,Sauguet, L. (登録日: 2022-07-01, 公開日: 2023-05-03, 最終更新日: 2024-05-01)

• 主引用文献: Madru, C.,Martinez-Carranza, M.,Laurent, S.,Alberti, A.C.,Chevreuil, M.,Raynal, B.,Haouz, A.,Le Meur, R.A.,Delarue, M.,Henneke, G.,Flament, D.,Krupovic, M.,Legrand, P.,Sauguet, L.; DNA-binding mechanism and evolution of replication protein A.; Nat Commun, 14:2326-2326, 2023; PubMed: 37087464; DOI: 10.1038/s41467-023-38048-w

実験手法

X-RAY DIFFRACTION (3.2 Å)