8A8U
Mycobacterium tuberculosis ClpC1 hexamer structure
Summary for 8A8U
| Entry DOI | 10.2210/pdb8a8u/pdb |
| Related | 8A8U 8A8V 8A8W |
| EMDB information | 15240 15241 15242 15243 |
| Descriptor | ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
| Functional Keywords | hexamer, tuberculosis, drug target, protein quality control, chaperone |
| Biological source | Mycobacterium tuberculosis More |
| Total number of polymer chains | 7 |
| Total formula weight | 574799.61 |
| Authors | Felix, J.,Fraga, H.,Gragera, M.,Bueno, T.,Weinhaeupl, K. (deposition date: 2022-06-24, release date: 2022-10-26, Last modification date: 2024-07-24) |
| Primary citation | Weinhaupl, K.,Gragera, M.,Bueno-Carrasco, M.T.,Arranz, R.,Krandor, O.,Akopian, T.,Soares, R.,Rubin, E.,Felix, J.,Fraga, H. Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298:102553-102553, 2022 Cited by PubMed: 36208775DOI: 10.1016/j.jbc.2022.102553 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.62 Å) |
Structure validation
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