8A4Y

SARS-CoV-2 non-structural protein-1 (nsp1) in complex with N-(2,3-dihydro-1H-inden-5-yl)acetamide

8A4Y の概要

• エントリーDOI: 10.2210/pdb8a4y/pdb
• 分子名称: Host translation inhibitor nsp1, N-(2,3-dihydro-1H-inden-5-yl)acetamide (3 entities in total)
• 機能のキーワード: sars-cov-2, non-structural protein-1, fragment hit, complex, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13284.38

構造登録者

Borsatto, A.,Galdadas, I.,Ma, S.,Damfo, S.,Haider, S.,Kozielski, F.,Estarellas, C.,Gervasio, F.L. (登録日: 2022-06-13, 公開日: 2022-11-23, 最終更新日: 2024-01-31)

• 主引用文献: Borsatto, A.,Akkad, O.,Galdadas, I.,Ma, S.,Damfo, S.,Haider, S.,Kozielski, F.,Estarellas, C.,Gervasio, F.L.; Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other beta-coronaviruses by simulations and crystallography.; Elife, 11:-, 2022; PubMed: 36412088; DOI: 10.7554/eLife.81167

実験手法

X-RAY DIFFRACTION (1.099 Å)