8A4I

Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA

8A4I の概要

• エントリーDOI: 10.2210/pdb8a4i/pdb
• 分子名称: Sal-like protein 4, DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), ZINC ION, ... (5 entities in total)
• 機能のキーワード: sall4, at-rich dna, okihiro syndrome, transcription factor, stem cell, dna binding protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 63141.39

構造登録者

Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G. (登録日: 2022-06-11, 公開日: 2023-01-11, 最終更新日: 2024-05-01)

• 主引用文献: Watson, J.A.,Pantier, R.,Jayachandran, U.,Chhatbar, K.,Alexander-Howden, B.,Kruusvee, V.,Prendecki, M.,Bird, A.,Cook, A.G.; Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome.; Life Sci Alliance, 6:-, 2023; PubMed: 36635047; DOI: 10.26508/lsa.202201588

実験手法

X-RAY DIFFRACTION (2.76 Å)