8A2C

The crystal structure of the S178A mutant of PET40, a PETase enzyme from an unclassified Amycolatopsis

8A2C の概要

• エントリーDOI: 10.2210/pdb8a2c/pdb
• 分子名称: PET40 S178A, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: petase, pet, enzyme, hydrolase, esterase, plastic, degradation, biotech, enzyme evolution
• 由来する生物種: unclassified Amycolatopsis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60382.20

構造登録者

Costanzi, E.,Applegate, V.,Port, A.,Smits, S.H.J. (登録日: 2022-06-03, 公開日: 2023-06-14, 最終更新日: 2024-06-26)

• 主引用文献: Zhang, H.,Dierkes, R.F.,Perez-Garcia, P.,Costanzi, E.,Dittrich, J.,Cea, P.A.,Gurschke, M.,Applegate, V.,Partus, K.,Schmeisser, C.,Pfleger, C.,Gohlke, H.,Smits, S.H.J.,Chow, J.,Streit, W.R.; The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).; Febs J., 291:70-91, 2024; PubMed: 37549040; DOI: 10.1111/febs.16924

実験手法

X-RAY DIFFRACTION (1.6 Å)