8A1Z
Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea
Summary for 8A1Z
| Entry DOI | 10.2210/pdb8a1z/pdb |
| Descriptor | Phosphoserine phosphatase, MAGNESIUM ION, 1-(2,4-dichlorophenyl)-3-oxidanyl-urea, ... (5 entities in total) |
| Functional Keywords | phosphoserine phosphatase, fragment, avium, hydrolase |
| Biological source | Mycobacterium avium 104 |
| Total number of polymer chains | 1 |
| Total formula weight | 44132.89 |
| Authors | Haufroid, M.,Wouters, J. (deposition date: 2022-06-02, release date: 2022-11-23, Last modification date: 2024-01-31) |
| Primary citation | Haufroid, M.,Volkov, A.N.,Wouters, J. Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach. Eur.J.Med.Chem., 245:114935-114935, 2022 Cited by PubMed: 36403421DOI: 10.1016/j.ejmech.2022.114935 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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