8A16
Human PTPRM domains FN3-4, in spacegroup P212121
Summary for 8A16
Entry DOI | 10.2210/pdb8a16/pdb |
Descriptor | Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | receptor phosphatase, homophilic dimer, cell adhesion |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 59768.34 |
Authors | Caroe, E.,Graham, S.C.,Sharpe, H.J.,Deane, J.E. (deposition date: 2022-05-31, release date: 2023-03-15, Last modification date: 2024-02-07) |
Primary citation | Hay, I.M.,Shamin, M.,Caroe, E.R.,Mohammed, A.S.A.,Svergun, D.I.,Jeffries, C.M.,Graham, S.C.,Sharpe, H.J.,Deane, J.E. Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299:102750-102750, 2023 Cited by PubMed: 36436563DOI: 10.1016/j.jbc.2022.102750 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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