8Y8Z

Structure of NET-Maprotiline in outward-open state

This is a non-PDB format compatible entry.

Summary for 8Y8Z

• Entry DOI: 10.2210/pdb8y8z/pdb
• EMDB information: 39064
• Descriptor: Sodium-dependent noradrenaline transporter, ~{N}-methyl-3-(1-tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2(7),3,5,9,11,13-hexaenyl)propan-1-amine, SODIUM ION, ... (5 entities in total)
• Functional Keywords: transporter, transport protein-inhibitor complex, transport protein/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 139444.79

Authors

Zhang, H.,Xu, E.H.,Jiang, Y. (deposition date: 2024-02-06, release date: 2024-05-29, Last modification date: 2024-07-03)

• Primary citation: Zhang, H.,Yin, Y.L.,Dai, A.,Zhang, T.,Zhang, C.,Wu, C.,Hu, W.,He, X.,Pan, B.,Jin, S.,Yuan, Q.,Wang, M.W.,Yang, D.,Xu, H.E.,Jiang, Y.; Dimerization and antidepressant recognition at noradrenaline transporter.; Nature, 630:247-254, 2024; PubMed: 38750358; DOI: 10.1038/s41586-024-07437-6

Experimental method

ELECTRON MICROSCOPY (3.29 Å)