8WTD

XBB.1.5.10 RBD in complex with ACE2

Summary for 8WTD

Entry DOI	10.2210/pdb8wtd/pdb
EMDB information	37832
Descriptor	Angiotensin-converting enzyme 2, Spike protein S2', 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov-2, xbb.1.5.10, ace2, rbd, viral protein, viral protein-protein binding complex, viral protein/protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	115990.05
Authors	Feng, L.L.,Feng, L.L. (deposition date: 2023-10-18, release date: 2023-12-13, Last modification date: 2024-03-20)
Primary citation	Jian, F.,Feng, L.,Yang, S.,Yu, Y.,Wang, L.,Song, W.,Yisimayi, A.,Chen, X.,Xu, Y.,Wang, P.,Yu, L.,Wang, J.,Liu, L.,Niu, X.,Wang, J.,Xiao, T.,An, R.,Wang, Y.,Gu, Q.,Shao, F.,Jin, R.,Shen, Z.,Wang, Y.,Wang, X.,Cao, Y. Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19:e1011868-e1011868, 2023 Cited by PubMed: 38117863 DOI: 10.1371/journal.ppat.1011868 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.06 Å)

Structure validation