8VRN
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ
This is a non-PDB format compatible entry.
Summary for 8VRN
Entry DOI | 10.2210/pdb8vrn/pdb |
EMDB information | 43485 |
Descriptor | Gamma-aminobutyric acid receptor subunit beta-2, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, PHOSPHATIDYLETHANOLAMINE, ... (13 entities in total) |
Functional Keywords | complex, pptq, drug modulation, gabaa receptor, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 372566.16 |
Authors | Chojnacka, W.,Teng, J.,Kim, J.J.,Jensen, A.A.,Hibbs, R.E. (deposition date: 2024-01-22, release date: 2024-06-26, Last modification date: 2024-07-03) |
Primary citation | Chojnacka, W.,Teng, J.,Kim, J.J.,Jensen, A.A.,Hibbs, R.E. Structural insights into GABA A receptor potentiation by Quaalude. Nat Commun, 15:5244-5244, 2024 Cited by PubMed: 38898000DOI: 10.1038/s41467-024-49471-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.57 Å) |
Structure validation
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