8VQB
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Summary for 8VQB
Entry DOI | 10.2210/pdb8vqb/pdb |
EMDB information | 43437 |
Descriptor | Spike protein S2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | sarbecoviruses, spike glycoprotein, fusion protein, prefusion-stabilized, seattle structural genomics center for infectious disease, ssgcid, viral protein |
Biological source | Sarbecovirus |
Total number of polymer chains | 3 |
Total formula weight | 211336.04 |
Authors | Lee, J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2024-01-18, release date: 2024-07-24) |
Primary citation | Lee, J.,Stewart, C.,Schafer, A.,Leaf, E.M.,Park, Y.J.,Asarnow, D.,Powers, J.M.,Treichel, C.,Sprouse, K.R.,Corti, D.,Baric, R.,King, N.P.,Veesler, D. A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nat Commun, 15:5496-5496, 2024 Cited by PubMed: 38944664DOI: 10.1038/s41467-024-49656-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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