8VAO

Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen

Summary for 8VAO

Entry DOI	10.2210/pdb8vao/pdb
EMDB information	43097
Descriptor	Spike protein S2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	sars-cov-2, spike protein, viral fusion, viral glycoprotein, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	3
Total formula weight	170961.32
Authors	Zhou, L.,McLellan, J.S. (deposition date: 2023-12-11, release date: 2024-07-10, Last modification date: 2024-09-18)
Primary citation	Nuqui, X.,Casalino, L.,Zhou, L.,Shehata, M.,Wang, A.,Tse, A.L.,Ojha, A.A.,Kearns, F.L.,Rosenfeld, M.A.,Miller, E.H.,Acreman, C.M.,Ahn, S.H.,Chandran, K.,McLellan, J.S.,Amaro, R.E. Simulation-driven design of stabilized SARS-CoV-2 spike S2 immunogens. Nat Commun, 15:7370-7370, 2024 Cited by PubMed: 39191724 DOI: 10.1038/s41467-024-50976-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation