8UM0

The structure of NanH in complex with Neu5,7,9Ac(2,6)-LAcNAc

Summary for 8UM0

Entry DOI	10.2210/pdb8um0/pdb
Descriptor	Sialidase, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-7,9-di-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ... (5 entities in total)
Functional Keywords	sialidase, hydrolase
Biological source	Clostridium perfringens ATCC 13124
Total number of polymer chains	1
Total formula weight	44463.30
Authors	Medley, B.J.,Boraston, A.B. (deposition date: 2023-10-17, release date: 2024-09-04, Last modification date: 2024-09-25)
Primary citation	Medley, B.J.,Low, K.E.,Irungu, J.D.W.,Kipchumba, L.,Daneshgar, P.,Liu, L.,Garber, J.M.,Klassen, L.,Inglis, G.D.,Boons, G.J.,Zandberg, W.F.,Abbott, D.W.,Boraston, A.B. A "terminal" case of glycan catabolism: structural and enzymatic characterization of the sialidases of Clostridium perfringens. J.Biol.Chem., :107750-107750, 2024 Cited by PubMed: 39251137 DOI: 10.1016/j.jbc.2024.107750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.46 Å)

Structure validation