8U4J

Structure of the HER4/BTC Homodimer Extracellular Domain

Summary for 8U4J

Entry DOI	10.2210/pdb8u4j/pdb
EMDB information	41883 41884 41885 41886
Descriptor	Receptor tyrosine-protein kinase erbB-4, Betacellulin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	receptor tyrosine kinase, membrane protein, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	158330.64
Authors	Trenker, R.,Diwanji, D.,Bingham, T.,Verba, K.A.,Jura, N. (deposition date: 2023-09-10, release date: 2024-03-13, Last modification date: 2024-09-25)
Primary citation	Trenker, R.,Diwanji, D.,Bingham, T.,Verba, K.A.,Jura, N. Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation. Elife, 12:-, 2024 Cited by PubMed: 38498590 DOI: 10.7554/eLife.92873 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation