8T99
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with Scyllo-L-1,4-[PP]2-(2,3)IP2, Mg, and Fluoride ion
Summary for 8T99
Entry DOI | 10.2210/pdb8t99/pdb |
Descriptor | Diphosphoinositol polyphosphate phosphohydrolase 1, (1R,2S,3S,4R,5S,6S)-2,3-dihydroxy-5,6-bis(phosphonooxy)cyclohexane-1,4-diyl bis[trihydrogen (diphosphate)], MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | inositol phosphate, inositol, phosphatase, nut3, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17938.22 |
Authors | Zong, G.,Wang, H.,Shears, S.B. (deposition date: 2023-06-23, release date: 2023-11-15, Last modification date: 2024-02-14) |
Primary citation | Zong, G.,Desfougeres, Y.,Portela-Torres, P.,Kwon, Y.U.,Saiardi, A.,Shears, S.B.,Wang, H. Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus. Embo J., 43:462-480, 2024 Cited by PubMed: 38216735DOI: 10.1038/s44318-023-00005-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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