8RVA

SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 7

This is a non-PDB format compatible entry.

Summary for 8RVA

• Entry DOI: 10.2210/pdb8rva/pdb
• Descriptor: 2'-O-methyltransferase nsp16, Non-structural protein 10, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: nsp16, nsp10, 2'-o-methyltransferase, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 49523.40

Authors

Kalnins, G. (deposition date: 2024-01-31, release date: 2024-02-14, Last modification date: 2024-10-02)

• Primary citation: Kalnins, G.,Rudusa, L.,Bula, A.,Zelencova-Gopejenko, D.,Bobileva, O.,Sisovs, M.,Tars, K.,Jirgensons, A.,Jaudzems, K.,Bobrovs, R.; Structural basis for inhibition of the SARS-CoV-2 nsp16 by substrate-based dual site inhibitors.; Chemmedchem, :e202400618-e202400618, 2024; PubMed: 39258386; DOI: 10.1002/cmdc.202400618

Experimental method

X-RAY DIFFRACTION (1.8 Å)