8QEB
S. cerevisia Niemann-Pick type C protein NCR1 in GDN at pH 7.5
Summary for 8QEB
Entry DOI | 10.2210/pdb8qeb/pdb |
Related | 8QEC 8QED 8QEE |
EMDB information | 18350 18351 18352 18353 |
Descriptor | NPC intracellular sterol transporter 1-related protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... (5 entities in total) |
Functional Keywords | sterol transport, vacuole, lysosome, lipid transport, membrane protein |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Total number of polymer chains | 1 |
Total formula weight | 135398.40 |
Authors | Frain, K.M.,Dedic, E.,Nel, L.,Olesen, E.,Stokes, D.,Panyella Pedersen, B. (deposition date: 2023-08-31, release date: 2023-10-18, Last modification date: 2024-04-17) |
Primary citation | Frain, K.M.,Dedic, E.,Nel, L.,Bohush, A.,Olesen, E.,Thaysen, K.,Wustner, D.,Stokes, D.L.,Pedersen, B.P. Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation. Proc.Natl.Acad.Sci.USA, 121:e2315575121-e2315575121, 2024 Cited by PubMed: 38568972DOI: 10.1073/pnas.2315575121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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