8QAE
X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix alpha-helical barrel, sc-apCC-6-SLLA
Summary for 8QAE
Entry DOI | 10.2210/pdb8qae/pdb |
Descriptor | sc-apCC-6-SLLA, 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, PENTAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | coiled coil, alpha-helical barrel, de novo protein design, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 53223.66 |
Authors | Albanese, K.I.,Petrenas, R.,Woolfson, D.N. (deposition date: 2023-08-22, release date: 2024-07-03, Last modification date: 2024-08-07) |
Primary citation | Albanese, K.I.,Petrenas, R.,Pirro, F.,Naudin, E.A.,Borucu, U.,Dawson, W.M.,Scott, D.A.,Leggett, G.J.,Weiner, O.D.,Oliver, T.A.A.,Woolfson, D.N. Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20:991-999, 2024 Cited by PubMed: 38902458DOI: 10.1038/s41589-024-01642-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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