8PVO
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FG5
Summary for 8PVO
Entry DOI | 10.2210/pdb8pvo/pdb |
Descriptor | Casein kinase II subunit alpha, SULFATE ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | kinase, ck2, allosteric inhibitor, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 84019.75 |
Authors | Kraemer, A.,Greco, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-07-18, release date: 2023-09-20, Last modification date: 2024-08-07) |
Primary citation | Greco, F.A.,Kramer, A.,Wahl, L.,Elson, L.,Ehret, T.A.L.,Gerninghaus, J.,Mockel, J.,Muller, S.,Hanke, T.,Knapp, S. Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276:116672-116672, 2024 Cited by PubMed: 39067440DOI: 10.1016/j.ejmech.2024.116672 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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