8PSH

HIGH RESOLUTION NMR STRUCTURE OF THE STEREOREGULAR (ALL-RP)-PHOSPHOROTHIOATE-DNA/RNA HYBRID D (G*PS*C*PS*G*PS*T*PS*C*PS*A*PS*G*PS*G)R(CCUGACGC), MINIMIZED AVERAGE STRUCTURE

Summary for 8PSH

• Entry DOI: 10.2210/pdb8psh/pdb
• Related: 8DRH
• Descriptor: DNA (5'-D(*DGP*(SC)P*(GS)P*(PST)P*(SC)P*(AS)P*(GS)P*(GS))-3'), RNA (5'-R(*CP*CP*UP*GP*AP*CP*GP*C)-3') (2 entities in total)
• Functional Keywords: oligonucleotide, dna-rna hybrid, phosphorothioate, thionucleotide, antisense
• Total number of polymer chains: 2
• Total formula weight: 5081.64

Authors

Bachelin, M.,Hessler, G.,Kurz, G.,Hacia, J.G.,Dervan, P.B.,Kessler, H. (deposition date: 1997-10-13, release date: 1998-05-27, Last modification date: 2022-03-16)

• Primary citation: Bachelin, M.,Hessler, G.,Kurz, G.,Hacia, J.G.,Dervan, P.B.,Kessler, H.; Structure of a Stereoregular Phosphorothioate DNA/RNA Duplex; Nat.Struct.Biol., 5:271-276, 1998; PubMed: 9546216; DOI: 10.1038/nsb0498-271

Experimental method

SOLUTION NMR