8PPW
Structure of human PARK7 in complex with GK16S
Summary for 8PPW
Entry DOI | 10.2210/pdb8ppw/pdb |
Descriptor | Parkinson disease protein 7, (3~{S})-1-(iminomethyl)-~{N}-pent-4-ynyl-pyrrolidine-3-carboxamide (3 entities in total) |
Functional Keywords | parkinson disease protein 7, cyanopyrrolidine, dj-1, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 20324.58 |
Authors | Grethe, C.,Gersch, M. (deposition date: 2023-07-10, release date: 2024-01-31, Last modification date: 2024-03-20) |
Primary citation | Schmidt, M.,Grethe, C.,Recknagel, S.,Kipka, G.M.,Klink, N.,Gersch, M. N-Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1. Angew.Chem.Int.Ed.Engl., 63:e202318849-e202318849, 2024 Cited by PubMed: 38239128DOI: 10.1002/anie.202318849 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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