8P5I

Kinase domain of mutant human ULK1 in complex with compound XMD-17-51

Summary for 8P5I

• Entry DOI: 10.2210/pdb8p5i/pdb
• Related: 8P5G
• Descriptor: Serine/threonine-protein kinase ULK1, 5,11-dimethyl-2-[(1-piperidin-4-ylpyrazol-4-yl)amino]pyrimido[4,5-b][1,4]benzodiazepin-6-one, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: autophagy, unc-like 1 kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 130549.86

Authors

Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05)

• Primary citation: Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P.; Crystal structures of ULK1 in complex with KCGS compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.829 Å)