8OYU

Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation

This is a non-PDB format compatible entry.

Summary for 8OYU

• Entry DOI: 10.2210/pdb8oyu/pdb
• EMDB information: 17296
• Descriptor: Spike glycoprotein,Fibritin, H6 nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: nanobody, complex, sars-cov-2, spike, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 5
• Total formula weight: 453656.75

Authors

Weckener, M.,Naismith, J.H.,Owens, R.J. (deposition date: 2023-05-05, release date: 2024-05-15, Last modification date: 2024-06-26)

• Primary citation: Cornish, K.,Huo, J.,Jones, L.,Sharma, P.,Thrush, J.W.,Abdelkarim, S.,Kipar, A.,Ramadurai, S.,Weckener, M.,Mikolajek, H.,Liu, S.,Buckle, I.,Bentley, E.,Kirby, A.,Han, X.,Laidlaw, S.M.,Hill, M.,Eyssen, L.,Norman, C.,Le Bas, A.,Clarke, J.,James, W.,Stewart, J.P.,Carroll, M.,Naismith, J.H.,Owens, R.J.; Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.; Open Biology, 14:230252-230252, 2024; PubMed: 38835241; DOI: 10.1098/rsob.230252

Experimental method

ELECTRON MICROSCOPY (4 Å)