8KFX
Gi bound CCR8 complex with nonpeptide agonist LMD-009
Summary for 8KFX
Entry DOI | 10.2210/pdb8kfx/pdb |
EMDB information | 37207 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr gi agonist, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 185465.23 |
Authors | |
Primary citation | Jiang, S.,Lin, X.,Wu, L.,Wang, L.,Wu, Y.,Xu, Z.,Xu, F. Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8. Sci Adv, 10:eadj7500-eadj7500, 2024 Cited by PubMed: 38306437DOI: 10.1126/sciadv.adj7500 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.96 Å) |
Structure validation
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