8JZS
Outward-facing SLC15A4 dimer
Summary for 8JZS
Entry DOI | 10.2210/pdb8jzs/pdb |
EMDB information | 36752 |
Descriptor | lysosomal transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL (3 entities in total) |
Functional Keywords | endolysosomal transporter, protein transport |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 134456.31 |
Authors | Zhang, S.S.,Chen, X.D.,Xie, M. (deposition date: 2023-07-06, release date: 2023-09-27, Last modification date: 2023-12-13) |
Primary citation | Chen, X.,Xie, M.,Zhang, S.,Monguio-Tortajada, M.,Yin, J.,Liu, C.,Zhang, Y.,Delacretaz, M.,Song, M.,Wang, Y.,Dong, L.,Ding, Q.,Zhou, B.,Tian, X.,Deng, H.,Xu, L.,Liu, X.,Yang, Z.,Chang, Q.,Na, J.,Zeng, W.,Superti-Furga, G.,Rebsamen, M.,Yang, M. Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14:6627-6627, 2023 Cited by PubMed: 37863913DOI: 10.1038/s41467-023-42210-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.95 Å) |
Structure validation
Download full validation report