8JPQ
SARS-CoV-2 Mpro in complex with D-5-96
Summary for 8JPQ
Entry DOI | 10.2210/pdb8jpq/pdb |
Descriptor | ORF1a polyprotein, ACETIC ACID, ALANINE, ... (5 entities in total) |
Functional Keywords | mpro, inhibitor, complex, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 33825.55 |
Authors | |
Primary citation | Liu, M.,Li, J.,Liu, W.,Yang, Y.,Zhang, M.,Ye, Y.,Zhu, W.,Zhou, C.,Zhai, H.,Xu, Z.,Zhang, G.,Huang, H. The S1'-S3' Pocket of the SARS-CoV-2 Main Protease Is Critical for Substrate Selectivity and Can Be Targeted with Covalent Inhibitors. Angew.Chem.Int.Ed.Engl., 62:e202309657-e202309657, 2023 Cited by PubMed: 37609788DOI: 10.1002/anie.202309657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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