8JNC
Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-maltophilin
Summary for 8JNC
Entry DOI | 10.2210/pdb8jnc/pdb |
Descriptor | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, (1Z,3E,5S,8R,9S,10S,11R,13R,15R,16S,18Z,24S,25S)-11-ethyl-2,24-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-7,20,27,28-tetraone, ... (6 entities in total) |
Functional Keywords | hydroxylation, polycyclic tetramate macrolactam, oxidoreductase, cytochrome p450 |
Biological source | Streptomyces sp. ZJ306 |
Total number of polymer chains | 2 |
Total formula weight | 94235.53 |
Authors | Zhang, Y.L.,Zhang, L.P.,Zhang, C.S. (deposition date: 2023-06-06, release date: 2023-11-15, Last modification date: 2023-12-20) |
Primary citation | Jiang, P.,Jin, H.,Zhang, G.,Zhang, W.,Liu, W.,Zhu, Y.,Zhang, C.,Zhang, L. A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62:e202310728-e202310728, 2023 Cited by PubMed: 37917570DOI: 10.1002/anie.202310728 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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