8JJC
Tubulin-Y62
Summary for 8JJC
Entry DOI | 10.2210/pdb8jjc/pdb |
Descriptor | Tubulin alpha-1B chain, GUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... (13 entities in total) |
Functional Keywords | microtubule, cell cycle |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 266461.77 |
Authors | |
Primary citation | Zhang, C.,Yan, W.,Liu, Y.,Tang, M.,Teng, Y.,Wang, F.,Hu, X.,Zhao, M.,Yang, J.,Li, Y. Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents. Eur.J.Med.Chem., 268:116265-116265, 2024 Cited by PubMed: 38430854DOI: 10.1016/j.ejmech.2024.116265 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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