8JJ0
Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab5F6 in one fab bind conformation
Summary for 8JJ0
Entry DOI | 10.2210/pdb8jj0/pdb |
EMDB information | 36336 |
Descriptor | Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 1, Fab5F6 Heavy Chain, ... (6 entities in total) |
Functional Keywords | nmdar, autoimmune encephalitis, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 434207.12 |
Authors | |
Primary citation | Wang, H.,Xie, C.,Deng, B.,Ding, J.,Li, N.,Kou, Z.,Jin, M.,He, J.,Wang, Q.,Wen, H.,Zhang, J.,Zhou, Q.,Chen, S.,Chen, X.,Yuan, T.F.,Zhu, S. Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39227720DOI: 10.1038/s41594-024-01387-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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