8J6J
Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound with GSK256073
Summary for 8J6J
Entry DOI | 10.2210/pdb8j6j/pdb |
EMDB information | 36006 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | hydroxycarboxylic acid receptor 2, gpcr, niacin, mk-6892, gsk256073, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 170881.43 |
Authors | |
Primary citation | Zhu, S.,Yuan, Q.,Li, X.,He, X.,Shen, S.,Wang, D.,Li, J.,Cheng, X.,Duan, X.,Xu, H.E.,Duan, J. Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell Rep, 42:113406-113406, 2023 Cited by PubMed: 37952153DOI: 10.1016/j.celrep.2023.113406 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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