8IZY
Human KCNQ2-CaM in complex with HN37
Summary for 8IZY
Entry DOI | 10.2210/pdb8izy/pdb |
EMDB information | 35877 |
Descriptor | Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate (2 entities in total) |
Functional Keywords | potassium voltage-gated channel, hn37, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 297234.38 |
Authors | |
Primary citation | Ma, D.,Zheng, Y.,Li, X.,Zhou, X.,Yang, Z.,Zhang, Y.,Wang, L.,Zhang, W.,Fang, J.,Zhao, G.,Hou, P.,Nan, F.,Yang, W.,Su, N.,Gao, Z.,Guo, J. Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14:6632-6632, 2023 Cited by PubMed: 37857637DOI: 10.1038/s41467-023-42416-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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