8IGF

Crystal Structure of Human Carbonic Anhydrase II In-complex with 4-Acetylphenylboronic acid at 2.6 A Resolution

Summary for 8IGF

• Entry DOI: 10.2210/pdb8igf/pdb
• Related: 3KS3
• Descriptor: Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: human carbonic anhydrase ii 4-acetylphenylboronic acid, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29350.17

Authors

Rasheed, S.,Huda, N.,Fisher, S.Z.,Falke, S.,Gul, S.,Ahmad, M.S.,Choudhary, M.I. (deposition date: 2023-02-20, release date: 2024-02-28, Last modification date: 2024-05-15)

• Primary citation: Rasheed, S.,Huda, N.U.,Fisher, S.Z.,Falke, S.,Gul, S.,Ahmed, M.S.,Choudhary, M.I.; Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II.; Int.J.Biol.Macromol., 267:131268-131268, 2024; PubMed: 38580011; DOI: 10.1016/j.ijbiomac.2024.131268

Experimental method

X-RAY DIFFRACTION (2.6 Å)