8HO0
Crystal structure of cytochrome P450 NasF5053 mutant E73S complexed with 8FCWP
Summary for 8HO0
Entry DOI | 10.2210/pdb8ho0/pdb |
Descriptor | Cytochrome P450-F5053, PROTOPORPHYRIN IX CONTAINING FE, (3~{S},8~{a}~{S})-3-[(7-fluoranyl-1~{H}-indol-3-yl)methyl]-2,3,6,7,8,8~{a}-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, ... (5 entities in total) |
Functional Keywords | p450, oxidoreductase |
Biological source | Streptomyces sp. NRRL F-5053 |
Total number of polymer chains | 1 |
Total formula weight | 44374.92 |
Authors | Ma, B.D.,Tian, W.,Qu, X.,Kong, X.D. (deposition date: 2022-12-09, release date: 2023-04-19, Last modification date: 2024-05-29) |
Primary citation | Sun, C.,Ma, B.D.,Li, G.,Tian, W.,Yang, L.,Peng, H.,Lin, Z.,Deng, Z.,Kong, X.D.,Qu, X. Engineering the Substrate Specificity of a P450 Dimerase Enables the Collective Biosynthesis of Heterodimeric Tryptophan-Containing Diketopiperazines. Angew.Chem.Int.Ed.Engl., 62:e202304994-e202304994, 2023 Cited by PubMed: 37083030DOI: 10.1002/anie.202304994 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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