8H06

Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement)

Summary for 8H06

• Entry DOI: 10.2210/pdb8h06/pdb
• EMDB information: 34409
• Descriptor: Processed angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: sars-cov-2, omicron ba.4/5, spike protein, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 93211.77

Authors

Zhao, Z.N.,Xie, Y.F.,Qi, J.X.,Gao, G.F. (deposition date: 2022-09-28, release date: 2023-07-19, Last modification date: 2023-08-02)

• Primary citation: Zhao, Z.,Xie, Y.,Bai, B.,Luo, C.,Zhou, J.,Li, W.,Meng, Y.,Li, L.,Li, D.,Li, X.,Li, X.,Wang, X.,Sun, J.,Xu, Z.,Sun, Y.,Zhang, W.,Fan, Z.,Zhao, X.,Wu, L.,Ma, J.,Li, O.Y.,Shang, G.,Chai, Y.,Liu, K.,Wang, P.,Gao, G.F.,Qi, J.; Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.; Nat Commun, 14:4405-4405, 2023; PubMed: 37479708; DOI: 10.1038/s41467-023-39942-z

Experimental method

ELECTRON MICROSCOPY (2.66 Å)