8GYD
Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16
Summary for 8GYD
Entry DOI | 10.2210/pdb8gyd/pdb |
Descriptor | Glutathione S-transferase class-mu 26 kDa isozyme, (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, ... (4 entities in total) |
Functional Keywords | complex, transferase |
Biological source | Schistosoma japonicum (Blood fluke) |
Total number of polymer chains | 2 |
Total formula weight | 56766.40 |
Authors | |
Primary citation | Wen, X.,Zhang, M.,Duan, Z.,Suo, Y.,Lu, W.,Jin, R.,Mu, B.,Li, K.,Zhang, X.,Meng, L.,Hong, Y.,Wang, X.,Hu, H.,Zhu, J.,Song, W.,Shen, A.,Lu, X. Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library. J.Med.Chem., 66:11118-11132, 2023 Cited by PubMed: 37552553DOI: 10.1021/acs.jmedchem.2c02129 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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