8GJN

17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer

Summary for 8GJN

Entry DOI	10.2210/pdb8gjn/pdb
EMDB information	40095
Descriptor	Heavy chain of 17B10 Fab, Light chain of 17B10 Fab, Spike protein S2', ... (4 entities in total)
Functional Keywords	viral protein
Biological source	Mus musculus (mouse) More
Total number of polymer chains	3
Total formula weight	51884.14
Authors	Kwon, H.J.,Zhang, J.,Kosikova, M.,Tang, W.C.,Rodriguez, U.O.,Peng, H.Q.,Meseda, C.A.,Pedro, C.L.,Schmeisser, F.,Lu, J.M.,Zhou, B.,Davis, C.T.,Wentworth, D.E.,Chen, W.H.,Shriver, M.C.,Pasetti, M.F.,Weir, J.P.,Chen, B.,Xie, H. (deposition date: 2023-03-16, release date: 2023-04-05, Last modification date: 2023-04-19)
Primary citation	Kwon, H.J.,Zhang, J.,Kosikova, M.,Tang, W.,Ortega-Rodriguez, U.,Peng, H.,Meseda, C.A.,Pedro, C.L.,Schmeisser, F.,Lu, J.,Kang, I.,Zhou, B.,Davis, C.T.,Wentworth, D.E.,Chen, W.H.,Shriver, M.C.,Barnes, R.S.,Pasetti, M.F.,Weir, J.P.,Chen, B.,Xie, H. Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95:e28673-e28673, 2023 Cited by PubMed: 36916782 DOI: 10.1002/jmv.28673 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation