8FRO
Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and a macrocyclic peptide
Summary for 8FRO
Entry DOI | 10.2210/pdb8fro/pdb |
EMDB information | 29400 29401 29402 29403 29404 |
Descriptor | Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, LPS export ABC transporter permease LptG, ... (5 entities in total) |
Functional Keywords | lipopolysaccharide, abc, atpase, antibiotic, macrocyclic peptide, gram-negative bacteria, eskape, lipid transport |
Biological source | Acinetobacter baylyi ADP1 More |
Total number of polymer chains | 4 |
Total formula weight | 143424.52 |
Authors | Pahil, K.S.,Gilman, M.S.A.,Kruse, A.C.,Kahne, D. (deposition date: 2023-01-07, release date: 2024-01-03, Last modification date: 2024-01-31) |
Primary citation | Pahil, K.S.,Gilman, M.S.A.,Baidin, V.,Clairfeuille, T.,Mattei, P.,Bieniossek, C.,Dey, F.,Muri, D.,Baettig, R.,Lobritz, M.,Bradley, K.,Kruse, A.C.,Kahne, D. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature, 625:572-577, 2024 Cited by PubMed: 38172635DOI: 10.1038/s41586-023-06799-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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