8FKF

Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR36706

Summary for 8FKF

• Entry DOI: 10.2210/pdb8fkf/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-N-(5-fluoropyridin-3-yl)-5-nitrobenzamide, ... (6 entities in total)
• Functional Keywords: nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 34651.42

Authors

MacTavish, B.S.,Kojetin, D.J. (deposition date: 2022-12-21, release date: 2024-04-17, Last modification date: 2024-10-09)

• Primary citation: MacTavish, B.S.,Kojetin, D.J.; Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR36706; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.82 Å)